Who is it for?

For those seeking to optimize their metabolism, longevity, and physical performance through scientifically supported strategies. Ideal for athletes, biohackers, and wellness professionals who aim to improve their body composition and vitality at the cellular level.

What it is

MOTS-c (Mitochondrial ORF of the Twelve S-c) is an endogenous peptide derived from mitochondrial DNA, composed of 16 amino acids. It acts as a metabolic signal that enhances insulin sensitivity, regulates fatty acid utilization, and stimulates mitochondrial oxidation, contributing to better energy control and higher cellular efficiency.

Why it matters

Natural MOTS-c expression declines with age and metabolic stress. Its exogenous administration restores mitochondrial adaptability, promoting a younger metabolism, greater resistance to fatigue, and visible improvements in body composition and overall well-being.

How it works

• Acts as a mitochondrial metabolic sensor activating the AMPK pathway.
• Stimulates fatty acid oxidation and reduces insulin resistance.
• Promotes a flexible and efficient metabolic state.
• Synergizes with mitochondrial biogenesis to slow metabolic aging.

What it does

• Enhances metabolic function and insulin sensitivity.
• Boosts cellular energy without adrenergic stimulation.
• Prevents age-related and oxidative metabolic decline.
• Supports body recomposition by promoting fat oxidation and muscular efficiency.

Key benefits

• Metabolic rejuvenation: activates AMPK and PGC-1α pathways, improving mitochondrial oxidative capacity.
• Improved body composition: enhances fat utilization as primary energy source and preserves lean mass.
• Enhanced physical and mental endurance: increases effort tolerance, recovery capacity, and cognitive clarity.