Description

What is LGD-4033?

LGD-4033 (also known as Ligandrol) is a SARM (Selective Androgen Receptor Modulator) originally developed by Ligand Pharmaceuticals. SARMs like LGD-4033 are used in bodybuilding as an alternative to anabolic steroids. Ligandrol has a high affinity for androgen receptors and is selective in that it only binds to receptors found in muscle and bone tissue.

LGD-4033 was initially developed to treat conditions such as muscle wasting (muscular dystrophy) caused by various diseases. It provides anabolic-like effects—muscle growth, joint and tendon support—with far fewer side effects than anabolic steroids (e.g., no high blood pressure, baldness, gynecomastia, acne, testicular atrophy, prostate enlargement, or liver toxicity).

What kind of results can be expected with LGD-4033?
An 8-week cycle of Ligandrol, combined with a proper diet and training plan, typically leads to 3 to 5 kg of lean muscle gains.

Is LGD-4033 suitable for women?
No. Ligandrol has androgenic effects and is therefore not recommended for women who want to avoid developing masculine traits. For women, Ostarine is a better choice.

Can LGD-4033 be used year-round?
No. LGD-4033 must be cycled. A minimum 4-week break is recommended between cycles.

Cycle duration:
6 to 8 weeks.

Recommended dosage:

• Low dose: 1 mg/day
• Moderate dose: 5 mg/day
• High dose: 8–10 mg/day (may increase side effect risk)

Does it affect the liver?
No. LGD-4033 is non-methylated and does not cause liver toxicity. No liver protection is required.

Best time of day to take Ligandrol?
Any time—it has a long half-life of 24–36 hours.

Does it affect estrogen levels?
No. LGD-4033 does not aromatize, so it doesn’t cause a significant increase in estrogen.

Does it increase blood pressure?
No.

Does it need to be taken on an empty stomach?
No. It works the same with or without food.

Are there any other side effects?
In rare cases, LGD-4033 may temporarily suppress natural testosterone production, especially with longer or high-dose cycles. This typically normalizes within 1–2 weeks.

Is post-cycle therapy (PCT) needed?
It may be helpful. To counteract possible testosterone suppression after longer or high-dose cycles, many users take a SERM like Toremifene or Raloxifene.

Can it help strengthen joints or aid injury recovery?
Yes, but Ostarine is generally more effective for this purpose.