Description

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What is KPV?

KPV is the C-terminal peptide fragment of the alpha-melanocyte-stimulating hormone (alpha-MSH).

KPV has potent anti-inflammatory activity in the central nervous system, gastrointestinal tract, lungs, cardiovascular system, immune system, and joints. It has also shown promise as a treatment for inflammatory bowel disease (IBD).

Since KPV is a short-chain peptide, its bioavailability is high and it can be administered in multiple ways, including orally.

KPV for inflammation and healing

KPV has the potential to reduce intestinal inflammation and provide faster recovery from certain intestinal disorders. KPV inhibits TNF-alpha and reduces the activity of mitogen-activated protein kinase and NF-kappaB (a protein complex that controls DNA transcription), thus helping to reduce inflammatory changes in the gut.

Studies show that KPV exerts its effect only in the presence of excessive inflammation and has little impact on non-inflamed tissue: KPV enters colon cells through PepT1, a protein channel that is only expressed in the intestine during inflammatory states.

Additionally, KPV also serves as a general anti-inflammatory. This is because alpha-MSH and several of its analogs reduce inflammation related to a wide variety of diseases such as dermatitis, vasculitis, fibrosis, and arthritis.

Likewise, the KPV promotes wound healing and may reduce the type of chronic inflammation that leads to hypertrophic scar formation, such as keloid scars.

Benefits of KPV

• Effectively combats various intestinal system disorders, such as inflammatory bowel disease (IBD)
• Has a powerful anti-inflammatory effect throughout the body
• Accelerates wound healing
• Helps prevent wounds from forming hypertrophic or keloid scars
• Regulates the immune system
• Has a powerful antimicrobial effect

Product presentation

Science.bio brand KPV vial (5mg)

Usual dosage

250mcg to 500mcg per day via subcutaneous (or oral) route.